La Educación Emocional en Primaria: Una revisión sistemática desde 2015 hasta 2017

This article presents a literature review of emotional education in elementary schools. The topic in question is considered of utmost importance. To this end, articles published on the Web of Science (WOS) during the years 2015, 2016 and 2017. The 37 selected articles, after cleaning up the data, were classified by subject for analysis according to whether they addressed the students or the teachers. Thirty-one of the earmarked documents investigated students and eight teachers. For the student documents, the articles were classified according to the role that emotional education played: as an end in itself, 18 articles, as a means, 12, and together with other variables, four documents. The articles intended for teachers focus on the initial training, as well as on the ongoing training, getting the results of the experience of these and of the development of emotional education in the classroom.Este artículo presenta una revisión bibliográfica sobre la educación emocional en primaria. Se considera de suma importancia la temática en cuestión. Se han buscado los artículos publicados en la Web of Science (2015-2017). Treinta y siete artículos fueron seleccionados: 31 sobre alumnado y 8 sobre docentes. Para los documentos de los discentes, se clasificaron los artículos según el papel que jugaba la educación emocional: como fin, 18 artículos, como medio, 12, o en correlación con otras variables, 4 documentos. Los artículos dedicados a los docentes, se centran en la formación inicial, así como en la formación permanente, obteniéndose resultados de la experiencia de estos y del desarrollo en el aula de la educación emocional. En conclusión, la educación emocional en la etapa primaria atañe tanto a docentes, como a alumnado, como medio o como fin. Cada vez está más estudiada. Y es una necesidad desarrollarla como eje transversal en las escuelas para contribuir a aumentar el bienestar

Predictive Biomarkers to Chemoradiation in Locally Advanced Rectal Cancer

There has been a high local recurrence rate in rectal cancer. Besides improvements in surgical techniques, both neoadjuvant short-course radiotherapy and long-course chemoradiation improve oncological results. Approximately 40–60% of rectal cancer patients treated with neoadjuvant chemoradiation achieve some degree of pathologic response. However, there is no effective method of predicting which patients will respond to neoadjuvant treatment. Recent studies have evaluated the potential of genetic biomarkers to predict outcome in locally advanced rectal adenocarcinoma treated with neoadjuvant chemoradiation. The articles produced by the PubMed search were reviewed for those specifically addressing a genetic profile’s ability to predict response to neoadjuvant treatment in rectal cancer. Although tissue gene microarray profiling has led to promising data in cancer, to date, none of the identified signatures or molecular markers in locally advanced rectal cancer has been successfully validated as a diagnostic or prognostic tool applicable to routine clinical practice

Periodistas de televisiones públicas vs. privadas: influencias percibidas y confianza en las instituciones políticas en España

Los objetivos de este artículo son estudiar los niveles de confianza en las instituciones políticas y las distintas fuentes de influencia percibidas por los periodistas de televisión en España. Además, se analizan las diferencias existentes entre quienes ejercen la profesión en las televisiones públicas y en las privadas. En el marco del proyecto internacional Worlds of Journalism Study y a través de una encuesta representativa a 390 periodistas españoles (70 de ellos de televisión), encontramos que quienes trabajan en las televisiones privadas confían más en el gobierno y que los periodistas de televisión reconocen mayores influencias políticas y organizativas que los profesionales de otros medios. Asimismo, observamos que en las televisiones privadas se muestran más influenciados por aspectos económicos y por los grupos de referencia que sus colegas de la televisión pública y que, en todos los casos, las influencias de las rutinas profesionales y las organizativas resultaron ser más altas que las políticas, económicas o de los grupos de referencia. Se explica cómo el tipo y propiedad del medio están relacionados con las percepciones sobre la propia cultura profesional. Se sugiere seguir profundizando en modelos que puedan explicar en mayor medida las varianzas encontradas en los dos tipos de percepciones

71-year-old male with anemia and loss of 10 kg of weight of 3 months of evolution

Varón de 71 años que ingresa por aumento progresivo de disnea y edematización de miembros inferiores de 2 semanas de evolución, con febrícula en las últimas 4 semanas. En la anamnesis destacaban episodios de diarrea que se alternaban con estreñimiento, astenia y pérdida de unos 10 kg de peso de 4 meses de evolución. En la exploración el paciente se encontraba afebril, las arterias temporales estaban engrosadas, no dolorosas ni arrosariadas y presentaba edemas blandos con fóvea hasta raíz de miembros. Tras un estudio exhaustivo con pruebas analíticas y de imagen, se fueron descartando patologías neoplásicas, infecciosas y endocrinas que permitieron realizar el diagnostico final.A 71-year-old male was admitted because of fever in the last 4 weeks with increasing dyspnea and lower limb oedema in the previous 2 weeks. In anamnesis of episode, the patient reported diarrhea alternating with constipation, asthenia and weight loss (about 10 kg) in the last 4 months. On examination, the patient was not feverish; temporal arteries were thickened but not painful or beaded; soft oedema reached to groins. Neoplastic, infectious and endocrine diseases were ruled out after an exhaustive study with laboratory tests and imaging. Finally, definitive diagnosis was reached

Afectación gastroduodenal como presentación inusual de la enfermedad de Crohn

It is relatively uncommon for Crohn’s disease to implicate the gastric and duodenal regions and occasionally it can cause pyloric stenosis, in which medical therapy may be ineffective and surgery might be required. We report two exceptional cases with prepyloric stenosis secondary to Crohn’s disease, aiming to emphasize the clinical suspicion and to describe the diagnostic imaging procedure and surgical treatments.Es relativamente infrecuente que la enfermedad de Crohs afecte al estomago y duodeno y ocasionalmente puede producir estenosis pilórica, en estas situaciones el tratamiento médico suele ser ineficaz y se requiere tratamiento quirúrgico. Se exponen dos casos clínicos excepcionales de estenosis prepilórica asociada a la enfermedad de Crohn, dirigidos a enfatizar en la sospecha clínica y describir el diagnóstico y el tratamiento quirúrgico

In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii

[Abstract] Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. Among them, the siderophore acinetobactin is one of the most important, being essential for the development of the infection. In this study we performed an in-depth analysis of the acinetobactin cluster in the strain A. baumannii ATCC 17978. For this purpose, nineteen individual isogenic mutant strains were generated, and further phenotypical analysis were performed. Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production. Similarly, the gene bauA, coding for the acinetobactin receptor, was also found to be crucial for the bacterial pathogenesis. In addition, the analysis of the ΔbasJ/ΔfbsB double mutant strain demonstrated the high level of genetic redundancy between siderophores where the role of specific genes of the acinetobactin cluster can be fulfilled by their fimsbactin redundant genes. Overall, this study highlights the essential role of entA, basG, basC, basD, basB and bauA in the pathogenicity of A. baumannii and provides potential therapeutic targets for the design of new antivirulence agents against this microorganism.This work was funded by Projects PI15/00860 awarded to GB and PI17/01482 to AB and MP, all within in the National Plan for Scientific Research, Development and Technological Innovation 2013–2016 and funded by the ISCIII – General Subdirection of Assessment and Promotion of the Research-European Regional Development Fund (FEDER) “A way of making Europe.” The study was also funded by project IN607A 2016/22 (GAIN- Agencia Gallega de Innovación – Consellería de Economía, Emprego e Industria) awarded to GB. This work was also supported by Planes Nacionales de I + D + i 2008–2011/2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía y Competitividad, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/006) co-financed by European Development Regional Fund “A way to achieve Europe” and operative program Intelligent Growth 2014–2020. This work was also supported by Grant RTI2018-093634-B-C22 (AEI/FEDER, EU) from the State Agency for Research (AEI) of Spain, co-funded by the FEDER Programme from the European Union and Xunta de Galicia for the support of Grant ED431E 2018/03 for CICA-INIBIC strategic and the initiative “Seed Projects 2019–2020.” JV-U was financially supported by the ISCIII project FI18/00315, LÁ-F by the ISCIII project PI14/00059 and the IN606B-2018/011, MM-G was financially supported by the Grant Clara Roy (SEIMC, Spanish Society of Clinical Microbiology and Infectious Diseases), KC-P by IN607A 2016/22 and AECC (Asociación Española Contra el Cáncer) predoctoral fellowship and LA by Xunta de Galicia co-funded with the European Social Fund (FSE) of the European Union (ED481A-2019/081)Xunta de Galicia; IN607A 2016/22Xunta de Galicia; ED431E 2018/03Xunta de Galicia; IN606B-2018/011Xunta de Galicia; IN607A 2016/22Xunta de Galicia; ED481A-2019/08

Heart Rate Variability monitoring during Interferential Current application in the lower back area : a cross-sectional study

[Abstract] Vasovagal reactions may occur occasionally during electrical stimulation using interferential current (IFC). The purpose of this study was to examine variations in autonomic activity during the application of IFC in asymptomatic participants by analysis of their heart rate variability (HRV). Seventy-three male volunteers were randomly assigned to a placebo group (n = 36; HRV was documented for 10 min, both at rest and during a placebo intervention) and an intervention group (n = 37; HRV was documented for 10 min in two conditions labelled as (1) rest and (2) application of IFC technique on the lumbar segment). The diameters of the Poincaré plot (SD1, SD2), stress score (SS), and the ratio between sympathetic and parasympathetic activity (S/PS) were measured. After interventions, differences amongst the placebo group and the IFC group were found in SD2 (p < 0.001), SS (p = 0.01) and S/PS ratio (p = 0.003). The IFC technique was associated with increased parasympathetic modulation, which could induce a vasovagal reaction. Monitorization of adverse reactions should be implemented during the application of IFC technique. HRV indicators might have a part in prevention of vasovagal reactions. Further studies in patients with lumbar pain are needed to explore possible differences in HRV responses due to the presence of chronic pai

Molecular dynamics simulation of CO2 hydrates: Prediction of three phase coexistence line

The three phase equilibrium line (hydrate-liquid water-liquid carbon dioxide) has been estimated for the water + carbon dioxide binary mixture using molecular dynamics simulation and the direct coexistence technique. Both molecules have been represented using rigid nonpolarizable models. TIP4P/2005 and TIP4P/Ice were used for the case of water, while carbon dioxide was considered as a three center linear molecule with the parameterizations of MSM, EPM2, TraPPE, and ZD. The influence of the initial guest occupancy fraction on the hydrate stability has been analyzed first in order to determine the optimal starting configuration for the simulations, paying attention to the influence of the two different cells existing in the sI hydrate structure. The three phase coexistence temperature was then determined for a pressure range from 2 to 500 MPa. The qualitative shape of the equilibrium curve estimated is correct, including the high pressure temperature maximum that determines the hydrate re-entrant behaviour. However, in order to obtain quantitative agreement with experimental results, a positive deviation from the classical Lorentz-Berthelot combining rules must be considered

Microarray profiling of mononuclear peripheral blood cells identifies novle candidate genes related to chemoradiation response in rectal cancer

Preoperative chemoradiation significantly improves oncological outcome in locally advanced rectal cancer. However there is no effective method of predicting tumor response to chemoradiation in these patients. Peripheral blood mononuclear cells have emerged recently as pathology markers of cancer and other diseases, making possible their use as therapy predictors. Furthermore, the importance of the immune response in radiosensivity of solid organs led us to hypothesized that microarray gene expression profiling of peripheral blood mononuclear cells could identify patients with response to chemoradiation in rectal cancer. Thirty five 35 patients with locally advanced rectal cancer were recruited initially to perform the study. Peripheral blood samples were obtained before neaodjuvant treatment. RNA was extracted and purified to obtain cDNA and cRNA for hybridization of microarrays included in Human WG CodeLink bioarrays. Quantitative real time PCR was used to validate microarray experiment data. Results were correlated with pathological response, according to Mandard´s criteria and final UICC Stage (patients with tumor regression grade 1–2 and downstaging being defined as responders and patients with grade 3–5 and no downstaging as non-responders). Twenty seven out of 35 patients were finally included in the study. We performed a multiple t-test using Significance Analysis of Microarrays, to find those genes differing significantly in expression, between responders (n = 11) and non-responders (n = 16) to CRT. The differently expressed genes were: BC 035656.1, CIR, PRDM2, CAPG, FALZ, HLA-DPB2, NUPL2, and ZFP36. The measurement of FALZ (p = 0.029) gene expression level determined by qRT-PCR, showed statistically significant differences between the two groups. Gene expression profiling reveals novel genes in peripheral blood samples of mononuclear cells that could predict responders and non-responders to chemoradiation in patients with locally advanced rectal cancer. Moreover, our investigation added further evidence to the importance of mononuclear cells’ mediated response in the neoadjuvant treatment of rectal cancer.This investigation was supported by the Fundación Investigación Biomédica Mutua Madrileña. MC, CC and AB were supported by projects P08-TIC-4299 and CTS2200 of Junta de Andalucía, TIN2009-13489 of DGICT, Madrid, and GREIB PYR_2010-02 and 2010_05 of University of Granada

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results